CyberDefender
CyberDefender is a full featured Internet security suite that protects PCs against fast moving threats. Discover infections other security software misses with protection from: spyware,viruses, spam, phishing, pop-ups, adware and Internet identity theft. Enjoy rapid detection and protection from fast-moving online security threats and full compatibility with other antivirus and security software products.
CyberDefender's patent pending earlyNETWORK is the world's first distributed system for security updates which detects and immunizes PCs against new virus attacks within hours after discovery. Each computer using the Early Detection Center is a part of the collaborative network solution. PCs on the CyberDefender network are on the lookout for suspicious files and relays them to the Early Alert Center which then quickly analyzes and provides threat definitions to update the entire network.
CyberDefender's Early Detection Center works while you do - with efficient scan speeds that won't slow down your system.
Key Features include:
Anti-Spyware removes more spyware and adware than McAfee, Trend Micro, Windows Live One Care and AVG
Anti-Virus detects, immunizes and remove virus infections 12 times faster than competing products
Anti-Spam shreds infected emails from Outlook and Outlook Express inboxes
Anti-Phishing analyzes, filters and blocks phishing scams and fake websites from your web surfing activity
Pop-Up Blocker blocks annoying pop-ups and adware. View only pop-ups you want to see with the history log.
100% FREE tech support via email and online
CyberDefender Early Detection Center is an award winning Internet security suite.
The software has been featured in the The San Francisco Chronicle, USA Today Online, About.com, Softonic.com, cNET, Tucows, PC Magazine, Tech Republic, eWEEK and numerous other publications.

Comments
I really like the Cyberdefender interface, scan times, and that it found what I know was on the system, including several programs/viruses/trojans that some of the others (PC Tools, SuperAntiVirus and Norton) missed. I used it as a free scanner, but the free version does remove spyware and trojan, but you got to upgrade for virus removal.
Eventually one came along, it caught it, and I bought the upgrade. Ran Cyberdefender after the upgrade, and virus was gone (it got into my rootkit and also got the vundo virus) which it took care of. I also like that the upgrade I got came with 24/7 computer help, which was very helpful when I went on a trip, and my wife had a printer problem and called them. They helped her out and had a positive experience with the Cyberdefender help line.
So, this is my experience with Cyberdefender - really good software. Granted, different people have different experiences, but this seems to be a good company (website says they are a NASDAQ company) with a valid product.